The placebo effect is when the effectiveness of a treatment is influenced by the patient’s perception of how effective they think the treatment will be, so a result might be seen even if the treatment...The placebo effect is when the effectiveness of a treatment is influenced by the patient’s perception of how effective they think the treatment will be, so a result might be seen even if the treatment is ineffectual. In a study about anti-depression medicine, you would not want the psychological evaluator to know whether the patient is in the treatment or control group either, as it might influence their evaluation, so the experiment should be conducted as a double-blind study.