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  • https://math.libretexts.org/Bookshelves/Applied_Mathematics/Mathematical_Biology_(Chasnov)/04%3A_Infectious_Disease_Modeling/4.06%3A_Evolution_of_Virulence
    Microorganisms continuously evolve due to selection pressures in their environments. Antibiotics are a common source of selection pressure on pathogenic bacteria, and the development of antibiotic-res...Microorganisms continuously evolve due to selection pressures in their environments. Antibiotics are a common source of selection pressure on pathogenic bacteria, and the development of antibiotic-resistant strains presents a major health challenge to medical science. Bacteria and viruses also compete directly with each other for reproductive success resulting in the evolution of virulence. Here, using the SIR endemic disease model, we study how virulence may evolve.

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