We can, however, introduce an additional variable \(D\), called the coefficient of linkage disequilibrium, and define \(D\) to be the difference between the gametic frequency \(p_{A B}\) and what this...We can, however, introduce an additional variable \(D\), called the coefficient of linkage disequilibrium, and define \(D\) to be the difference between the gametic frequency \(p_{A B}\) and what this gametic frequency would be if the loci were in linkage equilibrium: \[p_{A B}=p_{A} p_{B}+D \nonumber \] Using \(p_{A B}+p_{A b}=p_{A}\) to eliminate \(p_{A B}\) in (5.4.3), we obtain \[p_{A b}=p_{A} p_{b}-D \nonumber \] Likewise, using \(p_{A B}+p_{a B}=p_{B}\) \[p_{a B}=p_{a} p_{B}-D \nonumber \…
